To do or not to do? Is acetylsalicylic acid a safe drug to continue in bipolar turp? | [Bioscience Research • 2022]

Author(s):

1. Hamza Ashraf: Department of Urology, Tabba kidney institute, Karachi, Pakistan

2. Sharjeel Saulat: Department of Urology, Tabba kidney institute, Karachi, Pakistan

3. Syed Saeed Uddin Qadri: Department of Urology, Tabba kidney institute, Karachi, Pakistan

4. Jahanzeb Sheikh: Department of Urology, Tabba kidney institute, Karachi, Pakistan

5. Awais Ayub: Department of Urology, Tabba kidney institute, Karachi, Pakistan

6. Nauman Sadiq Kiani: Department of Urology, Tabba kidney institute, Karachi, Pakistan

7. Mansoor Ejaz: Department of Urology, Tabba kidney institute, Karachi, Pakistan

Abstract:

Benign prostatic hyperplasia is the fourth most commonly reported disease in elderly men (>50) following coronary heart disease, hypertension, and diabetes. This study aims to assess the effect of aspirin upon intraoperative & post-operative complications for TURP, one group with cessation of aspirin before procedure while the other one with the continuation of the medicine. This is a prospective, randomized Cohort study. The patients were randomly allocated within two groups, Group A had 40 patients who continued aspirin treatment during surgery and group B had 40 patients who had stopped taking aspirin the week before surgery. Data analysis was performed with the help of the statistical package of social sciences 22. The comparison of groups was analyzed as odds ratio and Student’s t-test. P-value of < 0.05 was considered significant. This study evaluated 80 patients, group A (on-aspirin) and group B (Off-aspirin) respectively. International prostate symptom score (IPSS) was filled before and after TURP, to assess the difference in results. The difference after TURP was significant with 37 (74%) and 38 (76%) patients in the mild symptoms category, 3 (6%) and 2 (4%) in moderate and none complaining of severe symptoms in group A and group B respectively. There was no significant difference in post-operative complications in both groups. Cessation of aspirin before transurethral resection of the prostate is not necessary and aspirin can be continued during surgery without any risk of complications such as bleeding, need for transfusion, adverse cardiovascular events, or hematuria.

Page(s): 1648-1654

DOI: DOI not available

Published: Journal: Bioscience Research, Volume: 19, Issue: 3, Year: 2022

Keywords:

Aspirin , Benign prostate hyperplasia , transurethral prostate resection

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