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Role of Vitamin D in Covid-19 Infection
Author(s):
1. Dua e Fathah: Department of Biochemistry, IBBB, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
2. Areeba Yousaf: Department of Biochemistry, IBBB, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
3. Mirza Imran Shahzad: Department of Biochemistry, IBBB, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
Abstract:
Initially, COVID- 19 occurs in 2019 in China, Wuhan and began to spread. The common indications of COVID-19 are cough, sore throat, fatigue, or dyspnea. Many drugs have been used to decrease the overwhelming results such as Ivermectin, Colchicine, Metformin, and Fluvoxamine are the most affected anti-parasite. Anti-parasitic drugs also contain some side effects. Numerous dietary tactics have been used but deficiency of vitamin D has been associated with an intensification in ICU treatment of patients infected with COVID-19. Past studies show that vitamin D has a role in the reduction of respiratory diseases in adults and children. Corona-viruses are enveloped by membranes or contain positive Single-Stranded RNA or have the ability to cause infection in equally animals and humans. S protein in the COVID- 19 binds to the ACE 2 receptor which leads to the entry of the virus into the body. A sufficient level of vitamin D in the host has been allied with amplified excretion of anti-microbial peptides or depressing the menace of hypercytokinemia, also tangled in the stimulation of macrophages i.e. defensive cells or protected response of TH2 cells.The central role of vitamin D in the human body is to sustain immunomodulatory, and calcium homeostasis and have anti-inflammatory, anti-fibrotic properties.Various studies have determined that there is no protagonist of vitamin D in managing of hazards of COVID-19. Thus, the objective of this paper is to clarify the immune-modulatory effects of vitamin D in the control of COVID-19.
Page(s): 98-98
DOI: DOI not available
Published: Journal: Abstract Book on Global Science Technology and Management Conference, Volume: 0, Issue: 0, Year: 2023
Keywords:
Vitamin D , COVID19 Infection
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