Synthesis, characterization and evaluation of a potential of piperidine substituted heterocyclic compounds | [Abstract Book on International Conference on Food and Applied Sciences (ICFAS-23) 3-5 August 23 • 2023]

Author(s):

1. Sadaf Naz: Dept. of Pharmaceutical Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi, Karachi, Pakistan

2. Shazia Haider: Dept. of Pharmaceutical Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi, Karachi, Pakistan

3. Muniba Inam: Dept. of Pharmaceutical Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi, Karachi, Pakistan

4. Ammara Khalid: Dept. of Pharmaceutical Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi, Karachi, Pakistan

Abstract:

During last few decades there have been extensive research work on Piperidine and Piperidine substituted compounds have been carried out to evaluate their potential as pharmacological and biologically active agents. A number of Piperidine substituted derivatives have been synthesized and characterized by different spectral techniques (EIMS, NMR, UV, FTIR). Analgesic potential of these compounds have been carried out using Eddy’s Hot Plate method and Acetic Acid induced Writhing test. Most of the compounds showed encouraging results, when compared to standard drug Pethidine Hydrochloride . This class can be selected for further studies at molecular level to completely screened its potential.

Page(s): 236-236

DOI: DOI not available

Published: Journal: Abstract Book on International Conference on Food and Applied Sciences (ICFAS-23) 3-5 August 23, Volume: 0, Issue: 0, Year: 2023

Keywords:

analgesic , piperidine , Writhing test , Eddys method , Pethidine Hydrochloride

References:

References are not available for this document.

Citations

Citations are not available for this document.

Citations

Downloads

Views