1,3-disubstituted ureas as antiglycating agents. | Journal of Chemical Society of Pakistan 2013

Author(s)

Shahnaz Perveen Pakistan Council of Scientific & Industrial Research (PCSIR) Laboratories Complex, Peshawar, Pakistan

Sana Mustafa Department of Chemistry, University of Karachi, Karachi, Pakistan

Khalid Mohammed Khan HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan

Muhammad Iqbal Choudhary HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan

Abstract

Twenty one (21) 1,3-disubstituted urea derivatives were screened for their antiglycating potential and some of them displayed promising activity. Compound N-butyl-N’-(4-nitrophenyl)urea (6) and N- isopropyl-N’-(4-nitrophenyl)urea (18) exhibited excellent activity and could be investigated in search of medicines treating diabetes and associated complications.

Publication Details

Page(s) 1605-1613

DOI DOI not available

Published Journal: Journal of Chemical Society of Pakistan, Volume: 35, Issue: 6, Year: 2013

Keywords

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