Warfarin continuation vs interruption during procedures of cardiac rhythm devices: a meta-analysis of randomized controlled trials. | [Journal of Pakistan Medical Association • 2016]

Author(s):

1. Huan Sun: Department of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, China

2. Beibei Du: Department of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, China

3. Xueyan Liu: Department of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, China

4. Sibao Yang: Department of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, China

5. Ping Yang: Department of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, China

Abstract:

To compare the safetyand efficacy of warfarin treatment continuation and heparin-bridging therapy during cardiac rhythm device (CRD) implantation in patients chronically treated with anticoagulants.We performed a search and analysis of peer-reviewed studies Four randomized controlled trials (RCTs)were included in our analysis with 941 patients. The bleeding risk in patients continuing warfarin perioperatively was lower than those interrupting warfarin and using a heparin-bridge (RD -0.08, 95% CI -0.17 to 0.02, p

Page(s): 458-463

DOI: DOI not available

Published: Journal: Journal of Pakistan Medical Association, Volume: 66, Issue: 4, Year: 2016

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