An assessment of coagulation parameters in liver cirrhosis. | [Biomedica • 2006]

Author(s):

1. Ahmad Hameed: Departments of Pathology and Heamatology, King Edward Medical College, Lahore, Pakistan

2. Samina Naeem: Departments of Pathology and Heamatology, King Edward Medical College, Lahore, Pakistan

3. A. Saeed Shaikh: Departments of Pathology and Heamatology, King Edward Medical College, Lahore, Pakistan

4. Irfan Khursheed: Departments of Pathology and Heamatology, King Edward Medical College, Lahore, Pakistan

5. Ambreen Hamid: Departments of Pathology and Heamatology, King Edward Medical College, Lahore, Pakistan

6. I. A. Naveed: Departments of Pathology and Heamatology, King Edward Medical College, Lahore, Pakistan

Abstract:

This study was carried out to assess the haemostatic defects in patients of liver cirrhosis by estimating prothrombin time (PT), activated partial thromboplastin time (APTT), plasma fibrinogen level, fibrinogen degradation products (D-dimer), and platelet count. It was carried out at the Department of Pathology, King Edward Medical College, Lahore. A total of 50 patients from all age groups of both gender with cirrhosis of liver were selected from Mayo Hospital, Lahore. All the investigations were carried out by standard procedures. Results were analyzed statistically with appropriate tests of significance. The mean values of PT and APTT were 14 second and 19 seconds longer than the control values respectively. These prolongations were highly significant statistically (p25o ng/ml. Mean platelet count in patients was significantly lower than normal value (p

Page(s): 74-77

DOI: DOI not available

Published: Journal: Biomedica, Volume: 22, Issue: 1, Year: 2006

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