The potential role of egfr in differentiating between true and pseudohyperkalemia at a tertiary care hospital | [Pakistan Journal of Pathology • 2023]

Author(s):

1. Syeda Sabahat Haider: Sheikh Zayed Hospital,Rahim Yar Khan,Pakistan

2. Rukhsana Tumrani: Sheikh Zayed Hospital,Rahim Yar Khan,Pakistan

3. Mehvish Sana: Sheikh Zayed Hospital,Rahim Yar Khan,Pakistan

4. Samreen Akhter: Sheikh Zayed Hospital,Rahim Yar Khan,Pakistan

5. Rabiya Mehmood: Sheikh Zayed Hospital,Rahim Yar Khan,Pakistan

6. Ume Farwa: Sheikh Zayed Hospital,Rahim Yar Khan,Pakistan

Abstract:

Objective: To determine the potential role of eGFR in differentiating between true and pseudohyperkalemia at a tertiary care hospital. Material and Methods: Cross-sectional study conducted in department of Chemical Pathology, Sheikh Zayed Hospital, Rahim Yar khan from January 1, 2022 to August 31, 2022. A total of 101 study subjects satisfying the inclusion criteria were included in study. Included specimen were analysed for serum creatinine level and estimated glomerular filtration rate (eGFR) was calculated by using chronic kidney disease-Epidemiology Collaboration (CKD-EPI) creatinine equation. Results: Of the total 101 study subjects, 59(58.4%) were male and 42(41.65%) were females. Mean age of study subjects was 45.28±12.265 years. Of the total 101 study samples, 75(74.3%) were classified as true hyperkalemia while 26(25.7%) were classified as pseudohyperkalemia with statistically significant difference of eGFR between two groups (P value: 0.00). Conclusion: Serum electrolytes are one of the most frequently requested diagnostic tests; thus, errors in these readings may alter the course of treatment for patients. As shown in our study that true hyperkalemia is very rare in patients with normal kidney function. So, estimated GFR can be taken as useful tool to differentiate between true and pseudohyperkalemia.

Page(s): 32-36

DOI: 10.55629/pakjpathol.v34i2.760

Published: Journal: Pakistan Journal of Pathology, Volume: 34, Issue: 2, Year: 2023

Keywords:

CKD , Pseudohyperkalemia , True hyperkalemia , Estimated GFR

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