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Exploring the effects of Chia (Salvia hispanica L.) mucilage against Hypertension in Hyperlipidemic patients
Author(s):
1. Muhammad Khurram Afzal:
2. Saeed Akhtar:
3. Tauseef Sultan:
4. Tariq Ismail:
5. Muhammad Naeem Zubairi:
6. Laraib Aziz Joher:
Abstract:
Previous studies have evaluated the effects of extracted oil and protein from chia seeds on non-communicable diseases including hypertension, but not a single study has examined the chia mucilage effect on human consumption. Therefore, the objective of the study was to explore the effects of chia mucilage supplementation for 4 weeks on blood pressure in hyperlipidemic individuals in a placebo-controlled trial. Chia mucilage was supplemented in wheat flour chapatis in 10 and 20% concentrations. 30 patients of hypertension and hyperlipidemia were provided with fortified chapatis for 4- weeks to meet the criteria of soluble dietary fiber, as governed by American Dietetic Association. Bp was measured weekly and Biochemical testing was performed before and after the study. Obtained results indicate that reduction in blood pressure was negligible in control and CMC-1 groups with 10% supplementation. But in the CMC-2 group reduction in blood pressure was negligible at the start but with the passage of time, it showed significant decrease in both SBP and DBP, 145.6 ± 4.5 to 142.4 ± 4.24mmHg and 104.2 ± 4.5 to 100 ± 3.9 mmHg, respectively. Significant improvements were also seen in lipid profile and fasting blood sugar in both experimental groups. Furthermore, chia mucilage supplemented chapati reduces the CRP, WBCs, and platelets due to the reduction in inflammation in the body but non-significant reduction in CK-MB, Urea, creatinine, ALT, and AST levels were observed. The study revealed the efficacy of chia mucilage supplementation in BP. Chronic studies are required to evaluate its pronounced effects.
Page(s): 1-1
DOI: DOI not available
Published: Journal: International Food & Nutrition Conference" August 18th-20th, 2022, University of Swat, Swat (Book of Abstracts), Volume: 1, Issue: 1, Year: 2022
Keywords:
Blood pressure , hyperlipidemia , Hypertension , chia soluble fiber , chia prebiotic , Chia polysaccharides , Chia mucilage
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