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The effect of Probiotic Yoghurt Consumption on Oxidative Stress and Inflammatory Factors in Young Females after Exhaustive Exercise.
Author(s):
1. Mohammad Mazani: Department of Clinical Biochemistry, School of Medicine, Ardabil University of Medical Sciences, Iran
2. Ali Nemati: Department of Clinical Biochemistry, School of Medicine, Ardabil University of Medical Sciences, Iran
3. Abbas Naghizadeh Baghi: Department of Exercise Physiology, University of Mohaghegh Ardabili, Ardabil University of Medical Sciences, Iran
4. Mojtaba Amani: Department of Clinical Biochemistry, School of Medicine, Ardabil University of Medical Sciences, Iran
5. Kobra Haedari: Department of Clinical Biochemistry, School of Medicine, Ardabil University of Medical Sciences, Iran
6. Reza AlipanahMogadam: Department of Clinical Biochemistry, School of Medicine, Ardabil University of Medical Sciences, Iran
Abstract:
Objective: To evaluate the effect of probiotic yoghurt consumption on oxidative stress and inflammatory factors in young females after exhaustive exercise. Method: This study included 27 healthy participants with an age range of 18-25. For two weeks, 450 grams of probiotic yoghurt and 450 grams of ordinary yoghurt were given to the supplement and control groups, respectively. Fasting blood samples were taken at baseline and at the end of study. At the end of the intervention, the participants were given one exhaustive exercise and then fasting blood samples were taken to test for blood antioxidant enzymes, inflammatory markers, and oxidative markers. Data were analyzed using descriptive statistics as well as paired and independent samples t-test. Results: In supplement group, the glutathione peroxidise (GPX) blood levels and serum levels of total antioxidant capacity (TAC) significantly increased at the end of two weeks of intervention (p<0.05). After intense physical activity, the blood levels of superoxide dismutase (SOD), GPX and serum levels of TAC significantly increased, whereas the serum level of tumour necrosis factor alpha (TNF-?), matrix metalloproteinase 2 (MMP2), matrix metalloproteinase 9 (MMP9), and malondialdehyde (MDA) significantly decreased in the supplement group compared to the control group (p<0.05). Besides, there were no significant changes in other biochemical factors. Conclusion: Regular probiotic yoghurt consumption significantly modulated MMP2, MMP9 and some inflammatory factors, and thus guarded against exhaustive exercise-inducing oxidative injury in young healthy females.
Page(s): 1748-1754
DOI: DOI not available
Published: Journal: Journal of Pakistan Medical Association, Volume: 68, Issue: 12, Year: 2018
Keywords:
oxidative stress , inflammation , Exhaustive exercise
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