Abstract:
Introduction: Vitiligo is an automimmune disease, characterized by depigmented patches involving variable surface area of skin. Immune modulating therapies like PUVA and systemic steroids are used in the management of vitiligo with variable results. Levamizole for its immunemodulating effects has been reported to be successful in the management of limited and slow progressing disease. It induces spontaneous repigmentation as well. Aims and objectives: The study was carried out with a view to determine the efficacy of levamizole in preventing disease progression and inducing spontaneous repigmentation in vitiligo. Material and methods: The study comprised of 22 patients belonging to either sex, aged 10 to 20 years. All the patients were given levamizole pulse therapy in a dose of 40mg TDS, on 2 continuous days per week for a period of 6 months. All the patients were followed up monthly to look for progression of the disease by Kobner phenomenon and any spontaneous repigmentation. Results: At the end of 6 months therapy, 16 (73%, p
Page(s):
12-17
DOI:
DOI not available
Published:
Journal: Journal of Pakistan Association of Dermatologists, Volume: 13, Issue: 7, Year: 2003