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The diagnostic dilemma of progressive muscular atrophy.
Author(s):
1. Saeed Bin Ayaz: Armed Forces Institute of Rehabilitation Medicine (AFIRM), Abid Majeed Road, Rawalpindi, Pakistan
2. Sumeera Matee: Armed Forces Institute of Rehabilitation Medicine (AFIRM), Abid Majeed Road, Rawalpindi, Pakistan
3. Zaheer Ahmed Gill: Armed Forces Institute of Rehabilitation Medicine (AFIRM), Abid Majeed Road, Rawalpindi, Pakistan
4. Atif Ahmed Khan: Armed Forces Institute of Rehabilitation Medicine (AFIRM), Abid Majeed Road, Rawalpindi, Pakistan
Abstract:
Progressive muscle atrophy is a rare subtype of motor neuron disease that affects only the lower motor neurons and presents as asymmetrical rapidly progressive muscle weakness, atrophy and normal sensations. The diagnostic electrophysiological findings are denervation potentials in three out of four body segments (bulbar, cervical, thoracic and lumbosacral). The disease is fatal and the management is supportive. We present the report of a 45-year-old female patient who presented with unilateral foot drop and rapidly progressed to profound weakness in muscles of all limbs, neck and back along with dysarthria and dysphagia. She had been operated twice for suspected cervical and lumbosacral intervertebral disc herniations and ultimately guided in right direction after muscle biopsy, nerve conduction studies and electromyography.
Page(s): 149-150
DOI: DOI not available
Published: Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 25, Issue: 2, Year: 2015
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