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A clinical manifestation of hepatitis c among the population of hyderabad, Pakistan
Author(s):
1. Mairaj Bibi: Institute of Biotechnology & Genetic Engineering, University of Sindh, Jamshoro, Pakistan
2. Asghar Ali Shaikh: Department of Chemistry, Government College University Hyderabad, Hyderabad 71000, Pakistan
3. Uroosa Sahar: Institute of Biotechnology & Genetic Engineering, University of Sindh, Jamshoro, Pakistan
4. Abdul Sajid: Department of Chemistry, Government College University Hyderabad, Hyderabad 71000, Pakistan
5. Santosh Kumar: Institute of Biotechnology & Genetic Engineering, University of Sindh, Jamshoro, Pakistan
6. Zameer Ali Palh: Department of Fresh Water Biology & Fisheries, University of Sindh, Jamshoro, Pakistan
7. Syed Habib Ahmed Naqvib: Institute of Biotechnology & Genetic Engineering, University of Sindh, Jamshoro, Pakistan
8. Shahla Karim Baloch: Department of Biotechnology, Sindh Agriculture University, Tandojam, Sindh, Pakistan
Abstract:
Hepatitis C is a noteworthy public health issue around the globe, resulting in liver-related problems. Almost 80% of HCV patients suffer from chronic circumstances and are likely to have liver ailments. Approximately 6% population of Pakistan is infected with HCV. In this study of 510 samples were collected from May 2022 to September 2022 from Hyderabad and adjacent areas. 291 out of 510 samples were affected by HCV. The collected samples were screened based on ELISA using recombinant HCV antigens. Biochemical and hematological factors were performed on HCV-infected patients. RBC, Hemoglobin, WBC, MCV, MCHC, and PLT were observed normally in all age groups. But WBC and PLT are high in the 10-20 age groups. Hematocrit and MCH were decreased as compared to normal levels. Bilirubin, SGPT, and Alkaline phosphate were high in some age groups but normal in other age groups. Albumin was found normal in all patients. These parameters were correlated to each other to know the causes and prevention of HCV.
Page(s): 193-207
Published: Journal: Pakistan Journal of Biotechnology, Volume: 20, Issue: 2, Year: 2023
Keywords:
Biochemical , Hepatitis C virus , Hematological , HCV Screening
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