Abstract:
Background: Antibiotic resistance is a growing global threat driven by antibiotic overuse. Antibiotic stewardship programs (ASPs) are a key strategy to optimize antibiotic prescribing and combat resistance. Objective: To systematically review the impact of ASPs on clinical and economic outcomes among hospitalized patients in Asia. Methods: We searched PubMed, Google Scholar, and PakMediNet for studies published in 2017-2021 that quantified ASP outcomes. Studies on costs, antibiotic use, length of stay, and mortality were included. Results: 18 studies met inclusion criteria. 13 (72%) reported decreased costs after ASP implementation, with net savings of up to $12,829 USD per patient. All studies showed reduced antibiotic use, especially carbapenems. 8 (44%) found shorter lengths of stay and 10 (56%) reported lower mortality rates with ASPs. Conclusions: ASPs improve clinical outcomes and reduce costs and antibiotic resistance in Asian hospitals. More research is needed on ASP knowledge and implementation in outpatient, primary, and secondary care settings.
Page(s):
128-132
DOI:
DOI not available
Published:
Journal: Journal of Society of Prevention, Advocacy and Research KEMU, Volume: 2, Issue: 3, Year: 2023