Author(s):
1. Ghulam Murtaza:
COMSATS University Islamabad, Pakistan.
2. Ali Akbar:
COMSATS University Islamabad, Pakistan.
3. Iftikhar Ahmed:
COMSATS University Islamabad, Pakistan.
Abstract:
This study develops a mathematical model for the transmission dynamics of the Chikungunya virus and explores strategies for its control. The model formulation includes the calculation of the basic reproduction number (R0) to assess disease persistence, and the impact of birth and death rates of Wolbachia infected mosquitoes is also examined. To control the outbreak, optimal control theory is applied using three interventions: release of Wolbachia-infected mosquitoes, release of sterile male mosquitoes, and public awareness campaigns. The resulting system of state and adjoint equations is solved numerically using the forward-backward sweep method. Simulation results are presented in detail for different scenarios, including single controls, double controls, combined controls, and the case without control. The comparative analysis confirms that the combined strategy yields the greatest reduction in infection levels, whereas single interventions are less effective. These findings emphasize that integrated vector management together with community-based approaches plays a crucial role in reducing the spread of Chikungunya. The study highlights how mathematical modeling and optimal control can provide valuable insights for designing practical strategies in global health management.
Page(s):
145-145
DOI:
DOI not available
Published:
Journal: 4th International Conference of Sciences “Revamped Scientific Outlook of 21st Century, 2025” , November 12,2025, Volume: 1, Issue: 1, Year: 2025
Keywords:
Wolbachia
,
Chikungunya
,
Sterile Insect Technique
,
mathematical modeling
,
Optimal Control
,
Basic Reproduction Number
References:
References are not available for this document.
Citations
Citations are not available for this document.