Abstract:
Objective: To examine the performance of rst-trimester visceral (pre-peritoneal), subcutaneous, and total adipose tissue thickness (ATT) to predict the patients with subsequently developing gestational Diabetes mellitus (GDM). Study Design: Observational study. Place and Duration of Study: Department of Obstetrics and Gynecology, Diyarbak1r Gazi Ya_argil Training and Research Hospital from January 2021 to July 2021. Methodology: A total of 100 pregnant women underwent sonographic measurement of subcutaneous and visceral ATT at 11-14 weeks gestation. A75-g oral glucose tolerance test (OGTT) was conducted between 24-28 weeks of pregnancy for the diagnosis of GDM. Results: The mean visceral, subcutaneous, and total ATT were signi cantly higher in the GDM group (24.75 ± 10.34 mm, 26.33 ± 5.33 mm, 51.08 ± 14.4 mm) than in the group without a GDM diagnosis (16.68 ± 6.73 mm, 17.68 ± 4.86 mm, 34.25 ± 11.04, respectively, p30 kg/m2 (Odds ratio [OR]=10.20, 95% CI=2.519-41.302, p=0.001), visceral ATT (OR=33.2, 95% CI=7.395-149.046, p<0.001), subcutaneous ATT (OR=4.543, 95% CI=1.149-17.960, p=0.031), and total ATT (OR=10.895, 95% CI=2.682-44.262, p=0.001) were the factors that were found to be signi cantly associated with the subsequent development of GDM after adjusting for potential confounders (maternal age, and parity). The most signi cant risk factor for the prediction of GDM is visceral ATT with an OR of 33.2. Conclusion: US measurement of maternal visceral ATT during rst-trimester fetal aneuploidy screening is a reliable, reproducible, cost-e ective, and safe method to identify pregnant women at high risk for GDM.
Page(s):
722-727
DOI:
DOI not available
Published:
Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 32, Issue: 6, Year: 2022
Keywords:
gestational diabetes mellitus
,
Visceral adipose tissue thickness
,
Subcutaneous adipose tissue thickness