A comparative study of prolactin and depressive symptoms in heroin addicts. | [International Journal of Pharmacology • 1990]

Author(s):

1. M. T. Aftab: Pharmacology Department, University of Karachi, Karachi, Pakistan

2. S. I. Ahmed: Pharmacology Department, University of Karachi, Karachi, Pakistan

3. E. M. Syed: National Research Institute of Fertility Care, Karachi, Pakistan

Abstract:

Changes in prolactin and depth of depression were studied in human heroin addicts. A proportional relation was observed in both. Disturbance in dopaminergic activity is suggested as a probable biochemical mechanism of depression in brain, which reflects itself as changes in prolactin levels of the body. The disturbance may be due to the direct or indirect effects of addiction at hypothalmic or pituitary level.

Page(s): 1-9

DOI: DOI not available

Published: Journal: International Journal of Pharmacology, Volume: 7, Issue: 1--2, Year: 1990

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