Tocolysis with ritodrine: A comparative study in preterm labour. | [Pakistan Journal of Medical Sciences • 2006]

Author(s):

1. Vijay Roy: Department of Pharmacy, Indraprastha Apollo Hospital, New Delhi, India

2. Gs Prasad: Department of Pharmacy, Annamalai University, Annamalai Nagar, Inda

3. K. Latha: Department of Obstetrics & Gynecology, Rajah Muthian Medical College & Hospital, Annamalai University, Annamalai Nagar, India

Abstract:

Preterm delivery is an important cause of perinatal morbidity and mortality. Thi study was conducted with an objective to assess the effect of ritodrine on perinatal mortality a compared to isoxsuprine and the effect of ritodrine on maternal morbidity and neonatal morbid ity in comparison to isoxsuprine with the extent to which delivery was delayed. A randomized study with 25 patients with ritodrine treatment (Group-1) and 25 patients to isoxsuprine treatment (Group-2) were studied. Setting: Rajah Muthiah Medical College and Hospital, Annamalai University, India. Tocolysis was reported to be successful for more than 72 hours in 96% in ritodrine grou and 84% in isoxsuprine group. Ritodrine was found superior because of lesser incidences of sid effects (56%) with ritodrine and (64%) with isoxsuprine, In terms of effectiveness of tocolysi number of patients failed cases were 16% with isoxsuprine when compared to 4% with ritodrine The mean birth weight of neonate was 3115.38 gm ± 642.3 in ritodrine groups and 2786.53 gm 673.43 is isoxsuprine group. Ritodrine is more efficacious in delaying delivery and increasing fetal maturity a compared to isoxsuprine.

Page(s): 64-69

DOI: DOI not available

Published: Journal: Pakistan Journal of Medical Sciences, Volume: 22, Issue: 1, Year: 2006

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