Abstract:
Herbs and spices are bio nutrients possessing significant nutritional and nutraceutical properties. Traditionally, these are considered as important culinary ingredients playing imperative role in food appreciation and acceptability. The prophylactic attributes of herbs and spices are of particular interest owing to the presence of several bioactive constituents. In theAsian cuisine, cumin and caraway seeds are extensively used in the ethnic dishes. The ancient ayurvedic, holistic and herbal preparations also contained these seeds as a preventive agent. Both these spices seems to be identical belonging to the family Apiaceae but play different physiological roles in the disease prevention and mitigation. Biochemical and pharmacological assessment of cumin and black caraway reveal constituents that possess array of compounds with health promoting potentials. For instance, Carum carvi L.- the black caraway commonly knownas Kala zeera contains carvone and limonene as major fractions. Investigations have revealed significant antioxidant potentials particularly due to the presence of carvone. On the other hand, cumin (Cuminum cyminum), also known as Safaid Zeera, is highly valued as a medicinal herb. The chief active constituents include cuminum and cuminaldehyde. Both these herbs are effective in alleviating the threat of lifestyle related dysfunctions. Caraway oil improves the pathology of diabetic nephropathy by increasing the natural antioxidant enzymes (e.g. glutathioneperoxidase) and scavenging the free radical species. It also possess restorative potential against hyperglycemia. The bio active component, carvone, exhibits numerous biological activities being antimicrobial, nematicidal, antidiabetic and antioncogenic in nature. It also inhibits the cholesterol biosynthesis by suppressing the HMG-COA activity in them evalonate cycle. Likewise, the cumin seed extract considerably decreases serum glucose level along side improving the insulin concentration. Dietary cuminand black car away supplementation is also helpful in preventing the incidence and progression of colon cancer. Moreover, oral cumin treatment exhibit immunomodulatory effects particularly through the modulation of T lymphocytes expression. Pharmacological activities of black caraway and cumin overwhelmingly substantiate their preferred use in diet based therapies. Besides, the understanding of natural products as alternatives to the conventional therapies, black car away and cumin seem well positioned assources of phytoceutics to boost the bioefficacy and bio availability of existing medicines.
Page(s):
356-356
DOI:
DOI not available
Published:
Journal: Abstract Book on International Conference on Food and Applied Sciences (ICFAS-23) 3-5 August 23, Volume: 0, Issue: 0, Year: 2023
Keywords:
cholesterol
,
cancer
,
glucose
,
black caraway
,
caravone
,
Cumin
,
Cuminaldehyde