Thrombocytopenia in malaria | [Journal of College of Physicians and Surgeons--Pakistan : JCPSP • 2009]

Author(s):

1. Qurban Hussain Shaikh: Department of Medicine, Jinnah Postgraduate Medical Centre, Karachi, Pakistan

2. Syed Masroor Ahmad: Department of Medicine, Jinnah Postgraduate Medical Centre, Karachi, Pakistan

3. Amanullah Abbasi: Department of Medicine, Jinnah Postgraduate Medical Centre, Karachi, Pakistan

4. Shujaat Ali Malik: Department of Medicine, Baqai University Hospital, Karachi, Pakistan

5. Abdul Aziz Sahito: Department of Medicine, Jinnah Postgraduate Medical Centre, Karachi, Pakistan

6. S.M. Munir: Department of Medicine, Jinnah Postgraduate Medical Centre, Karachi, Pakistan

Abstract:

Objective: To determine the frequency of thrombocytopenia in Malarial Parasite (MP) positive patients. Study Design: A cross-sectional study. Place and Duration of Study: Medical Unit-III, Ward-7, JPMC, Karachi, from June to October 2006. Methodology: One hundred twenty four MP positive cases were included in the study. Infections with both Plasmodium falciparum and Plasmodium vivax species were included. Complete blood picture with platelet count was obtained in all patients. Thrombocytopenia was defined as platelets count of < 150,000/cmm. Results: Among 124 patients of MP positive, 100 (80.6%) were found to have thrombocytopenia. Over all 64 patients had Plasmodium falciparum, while 60 patients were having Plasmodium vivax infection. The frequency of thrombocytopenia was 71.87% (n=46) in falciparum and 93.33% (n=56) in vivax infection. Conclusion: Thrombocytopenia was a common haematological finding in patients with Plasmodium infection particularly marked in vivax species nfection.

Page(s): 708-710

DOI: DOI not available

Published: Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 19, Issue: 11, Year: 2009

Keywords:

Malaria Thrombocytopenia Plasmodium vivax Plasmodium falciparum

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