Zinc deficiency and supplementation in ovariectomized rats: their effect on serum estrogen and progesterone levels and their relation to calcium and phosphorus. | [Pakistan Journal of Pharmaceutical Sciences • 2009]

Author(s):

1. Fusus Sunar: Selcuk University Meram Medical School Department of Physiology, Konya, Turkey

2. Abdulkerim Kasim Baltaci: Selcuk University Meram Medical School Department of Physiology, Konya, Turkey

3. Neyhan Ergene: Selcuk University Meram Medical School Department of Physiology, Konya, Turkey

4. Rasim Mogulkoc: Selcuk University Meram Medical School Department of Physiology, Konya, Turkey

Abstract:

The aim of this study is to examine how zinc deficiency or supplementation affects estrogen and progesterone and calcium and phosphorus levels in the serum. The study was carried out on 40 adult female rats of Sprague-Dawley species. The rats were allocated to four groups: Group 1: Control, Group 2: Ovariectomized (OVX) control. Group 3: OVX-Zinc-supplemented. Group 4: OVX-Zinc-deficient. Blood samples were taken from the experimental animals by decapitation method and analyzed in terms of estrogen, progesterone, calcium, phosphorus, magnesium and zinc levels. Group 1 had the highest estrogen levels (p

Page(s): 150-154

DOI: DOI not available

Published: Journal: Pakistan Journal of Pharmaceutical Sciences, Volume: 22, Issue: 2, Year: 2009

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