Tuberculous meningitis and hydrocephalus treated successfully with a combination of immunomodulation and cerebrospinal fluid diversion. | [Infectious Diseases Journal • 2007]

Author(s):

1. S. H. Aliyu: Department of Infectious Diseases, Addenbrooke`s Hospital, Cambridge, U.K

2. D. Ganesan: Department of Neurosciences, Addenbrooke`s Hospital, Cambridge, U.K

3. D A. Enoch: Clinical Microbiology and Public Health Laboratory, Health Protection Agency, Addenbrooke`s Hospital, Cambridge, U.K

4. C. Watts: Clinical Microbiology and Public Health Laboratory, Health Protection Agency, Addenbrooke`s Hospital, Cambridge, U.K

5. A. M. L. Lever: Clinical Microbiology and Public Health Laboratory, Health Protection Agency, Addenbrooke`s Hospital, Cambridge, U.K

Abstract:

The management of tuberculous meningitis with hydrocephalus is complex with most centres advocating ventriculoperitoneal shunting only in the presence of raised CSF pressure. This article reports a case of tuberculous meningitis with hydrocephalus treated with a combination of early surgical and immunomodulatory therapy in addition to conventional steroids and antituberculous agents. This case demonstrates that during the early phase of tuberculous meningitis with hydrocephalus, a combined multi-disciplinary approach will help prevent neuronal injury due to progressive ventricular enlargement and inflammation.

Page(s): 22-24

DOI: DOI not available

Published: Journal: Infectious Diseases Journal, Volume: 16, Issue: 1, Year: 2007

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