Analgesic activities of ethanol extract of leaf stem and their different fractions of Swertia chirata. | [Pakistan Journal of Pharmaceutical Sciences • 2010]

Author(s):

1. Khondoker Dedarul Alam: Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Bangladesh

2. Mohammad Shawkat Ali: Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Bangladesh

3. Salma Parvin: Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Bangladesh

4. Mohammad Ahsan-Ul-Akbar: Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Bangladesh

5. Rubina Ahmed: Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Bangladesh

6. Sanjida Mahjabeen: Department of Pharmaceutical Technology, University of Dhaka, Bangladesh

Abstract:

The purpose of the present study was to investigate the analgesic activity of ethanol extract of leaf, stem, and their different fractions i.e. pet-ether, dichloromethane, and methanol fraction of Swertia chirata (Family- Gentianaceae) on Swiss albino mice. Acetic acid induced writhing in mice was used as the process to evaluate the analgesic activity. The ethanol extract of leaf and stem of Swertia chirata showed moderate inhibition (p

Page(s): 455-457

DOI: DOI not available

Published: Journal: Pakistan Journal of Pharmaceutical Sciences, Volume: 23, Issue: 4, Year: 2010

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