The oxidative and antioxidative status of simple febrile seizure patients. | [Journal of Pakistan Medical Association • 2013]

Author(s):

1. Mahmut Abuhandan: Department of Paediatrics, Harran University, Sanliurfa, Turkey

2. Mustafa Calik: Department of Paediatric, Harran University, Sanliurfa, Turkey

3. Abdullah Taskin: Department of Clinical Biochemistry, Harran University, Sanliurfa, Turkey

4. Ilhan Yetkin: Department of Paediatrics, Harran University, Sanliurfa, Turkey

5. Sahabettin Selek: Department of Clinical Biochemistry, Harran University, Sanliurfa, Turkey

6. Akin Iscan: Department of Paediatric, Harran University, Sanliurfa, Turkey

Abstract:

Objective: To evaluate the oxidative status following a seizure in children experiencing a simple febrile seizure. Methods: The cross-sectional study was conducted at Harran University, Turkey, between January and September 2011. It comprised 32 paediatric patients who, within the preceding 8 hours, had experienced a seizure due to upper respiratory tract infection and had been diagnosed with simple febrile seizure, and 30 healthy children as the control group. Blood was taken from the patients 8 hours after the seizure. Total oxidant level and Total anti-oxidant level were measured according to the Erel technique and the oxidative stress index was calculated. Data was analysed using SPSS 11.5. Results: The mean values of the total oxidant level and the oxidative stress index of the cases were found to be significantly high compared to the controls and the total anti-oxidant level was found to be significantly low (p

Page(s): 594-597

DOI: DOI not available

Published: Journal: Journal of Pakistan Medical Association, Volume: 63, Issue: 5, Year: 2013

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