A study of renal tumours in tertiary care hospitals. | [Biomedica • 2014]

Author(s):

1. S M. Zain Mehdi: University of Health Sciences, Lahore, Pakistan

2. Nadia Naseem: University of Health Sciences, Lahore, Pakistan

3. Safdar Sial: Sheikh Zayed Hospital, Lahore, Pakistan

4. Rana Qaiser Mehmood: Punjab Medical College, Faisalabad, Pakistan

5. Aman-Ur-Rehman: Punjab Medical College, Faisalabad, Pakistan

6. Imran Qadir: Punjab Medical College, Faisalabad, Pakistan

7. A. H Nagi: University of Health Sciences, Lahore, Pakistan

Abstract:

Introduction: Renal cell carcinomas (RCC) comprise 90% of all renal tumours and are presage of poor outcome. Very little data has been published in Pakistan regarding the clinical and pathological manifestations of the disease. Materials and Methods: A total of 50 cases presenting with different subtypes of RCC were selected from Allied Hospital Faisalabad and Sheikh Zayed Hospital, Lahore. Clinical details were obtained from the hospital records. The fresh nephrectomy specimens were further processed according to College of American Pathologists guidelines. Results: Mean age of the study population was 50.16 ± 11.982 years. Male to female ratio was 2.57:1. Left to right ratio was 1:1. Most tumours (n = 36, 72%) were located in the upper pole. Most common symptom was heamaturia (n = 38, 76%). Mean of the greatest dimension was 10.41 ± 4.22 cm. The most common stage of presentation was stage II (n = 21, 42%) and histological subtype was clear cell carcinoma (n = 37, 74%). Conclusion: Renal cell carcinoma, including its chromophobe variant, is a growing malignancy in Pakistan. Delay in seeking medical care on the part of patient and inadequate facilities account for the tumour growing to a larger size and more advanced stage of malignancy in our country.

Page(s): 48-52

DOI: DOI not available

Published: Journal: Biomedica, Volume: 30, Issue: 1, Year: 2014

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