The value of CA15-3 in diagnosis, prognosis and treatment response in women with breast cancer. | [Journal of Pakistan Medical Association • 2013]

Author(s):

1. Hiba Qassem Ali: Department of Microbiology, Department of Surgery, College of Medicine, University of Basrah, Basrah, Iraq

2. Nadham Kadham Mahdi: Department of Microbiology, Department of Surgery, College of Medicine, University of Basrah, Basrah, Iraq

3. Mohammad Husein Al-Jowher: Department of Surgery, College of Medicine, Basrah, Iraq

Abstract:

Objective: To evaluate the role of cancer antigen CA15-3 in the diagnosis, prognosis, followup and treatment of breast cancer. Methods: The case-control study was done from October 2009 to February 2011 at the Al-Basrah Hospital in Basrah, Iraq. Blood samples were collected from 30 women with primary breast cancer before the invasive procedure. Another set of blood samples were collected from 23 of the cases after three cycles of chemotherapy. Besides, 20 serum samples were collected from apparently healthy women as a control group from the outpatient department. Enzyme-linked immunosorbent assay (ELISA) test was used for detection of serum CA15-3. Results: Mean CA15-3 level for the cases (79.15±27.54U/ml) was significantly higher than the controls (24.34±11.68U/ml) (p

Page(s): 1138-1141

DOI: DOI not available

Published: Journal: Journal of Pakistan Medical Association, Volume: 63, Issue: 9, Year: 2013

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