A comparison Between Intravenous Metoprolol and Labetalol in Prevention of Cardiovascular Stress Response to Laryngoscopy and Intubation. | [Anaesthesia, Pain and Intensive Care • 2018]

Author(s):

1. NisheeR Swami: Department of Anesthesiology and Critical Care, Pravara Institute of Medical Sciences, Loni, India

2. Vaishalee K Badhe: Department of Anesthesiology and Critical Care, Pravara Institute of Medical Sciences, Loni, India)

3. Vaishali V Deshpande: Department of Anesthesiology, Seth Nandlal Dhoot Hospital, Aurangabad, India

4. Vaijayanti K Badhe: Department of Anesthesiology and Critical Care, Pravara Institute of Medical Sciences, Loni, India

5. Shidhaye Ramchandra Vinayak: Department of Anesthesiology and Critical Care, Pravara Institute of Medical Sciences, Loni, India

Abstract:

Introduction: A prospective, randomized, double blind, clinical study was designed to compare intravenous metoprolol 30 µg/kg versus intravenous labetalol 0.2 mg/kg single Department of Anesthesiology dose given 5 min prior to intubation in for prevention of cardiovascular stress response and Critical Care, Pravara Institute of Medical Sciences, to laryngoscopy and intubation in patients undergoing spine surgeries under general Loni 413736 (India) anesthesia. 2Professor / Head, Department Methodology: Sixty ASA grade I patients of either sex , comprising age group of 25of Anesthesiology, Seth 50 years , undergoing elective spine surgeries under general anesthesia were randomly Nandlal Dhoot Hospital, distributed in two equal groups. Inj metoprolol hydrochloride 30 µg/kg in Group M and Aurangabad (India) inj labetalol 0.2 mg/kg in Group L respectively were given intravenously 5 min prior to induction. Heart rate, systolic, diastolic and MBP recorded at different time intervals before and after intubation. Conclusion: Labetalol is superior to metoprolol in attenuating the cardiovascular stress response to laryngoscopy and intubation.

Page(s): 180-186

DOI: DOI not available

Published: Journal: Anaesthesia, Pain and Intensive Care, Volume: 22, Issue: 2, Year: 2018

Keywords:

Presser response , Metoprolol , Laryngoscopy , Tracheal intubation

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