The Prevalence of Low Vitamin D3 Levels in Patients with Lumbar Disc Herniation and Its Relationship with Different Patient Parameters | [Pakistan Journal of Neurological Surgery • 2022]

Author(s):

1. Rabail Akbar Qazi: Department of Neurosurgery, Jinnah Postgraduate Medical Centre (JPMC), Karachi, Pakistan

2. Lal Rehman: Department of Neurosurgery, Jinnah Postgraduate Medical Centre (JPMC), Karachi, Pakistan

3. Farrukh Javeed: Department of Neurosurgery, Jinnah Postgraduate Medical Centre (JPMC), Karachi, Pakistan

4. Sana Akbar Qazi: Department of Neurosurgery, Jinnah Postgraduate Medical Centre (JPMC), Karachi, Pakistan

5. Tanweer Ahmed: Department of Neurosurgery, Jinnah Postgraduate Medical Centre (JPMC), Karachi, Pakistan

6. Asad Abbas: Nottingham University Hospital, Queen’s Medical Centre Campus, UK

Abstract:

Objective: To determine the prevalence of low vitamin D3 levels in patients having proven lumbar disc herniation and its relationship with different patient parameters. Materials and Methods: This is a prospective study carried out on 100 patients at the Neurosurgery department, Jinnah postgraduate medical center from Feb 2018 to April 2019. Serum Vitamin D levels and other characteristics were assessed in patients with prolapsed lumbar intervertebral discs. Low levels of Vitamin D were defined as insufficiency (10 ng/ml - 30 ng/ml) and deficiency (< 10 ng/ml). Results: Out of 100 patients in the study, only 21% had optimal serum vitamin D3 levels, and 79% had hypovitaminosis (57% insufficient and 22% deficiency). Low vitamin D levels were prevalent in all age groups, with deficiency more prevalent in the older age group (p-value = 0.004). The BMI (body mass index) of the patients showed a linear correlation with vitamin D levels. Conclusion: Decreased vitamin D levels are prevalent in patients having herniated lumbar discs. The study showed that older-aged patients and high BMI exhibited severe vitamin D deficiency. As a result, recommendations are that preventive initiative for this specific hypovitaminosis target a broader population to intercept the occurrence of low vitamin D levels and the associated repercussions.

Page(s): 229-235

DOI: 10.36552/pjns.v26i2.637

Published: Journal: Pakistan Journal of Neurological Surgery, Volume: 26, Issue: 2, Year: 2022

Keywords:

Vitamin D , Hypovitaminosis , Prolapsed intervertebral disc

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