Abstract:
Metal-organic frameworks (MOFs) are highly porous, crystalline materials composed of metal ions or clusters coordinated with organic ligands, offering tunable structures and exceptional surface areas. Their versatility has positioned them as transformative materials in diverse applications, including gas adsorption, drug delivery, and catalysis, in between many others. In gas adsorption, MOFs excel due to their high porosity and customizable pore chemistry. Their large surface areas, often exceeding 5000 m²/g, enable efficient capture and storage of gases such as CO2, CH4, and H2. Functionalized MOFs, tailored with specific ligands, enhance selectivity and capacity, making them promising materials for carbon capture, natural gas storage, and hydrogen fuel technologies. Their structural stability and recyclability further bolster their practical utility. For drug delivery, MOFs offer a biocompatible platform with controlled release capabilities. Their tunable pore sizes and high loading capacities allow encapsulation of diverse therapeutic agents, from smallmolecule drugs to biological macromolecules. Surface modifications enable targeted delivery and stimuli-responsive release, improving therapeutic efficacy while minimizing side effects. Biodegradable MOFs, such as those based on zinc or iron, are particularly promising for biomedical applications, demonstrating low toxicity and compatibility with physiological environments. In catalysis, MOFs serve as highly efficient catalysts due to their well- defined active sites and porous structures, which facilitate reactant accessibility and product diffusion. Functionalized MOFs, incorporating metal nanoparticles or enzymes, enable applications in organic synthesis, pollutant degradation, and energy conversion processes like water splitting and CO2 reduction. Their ability to combine homogeneous and heterogeneous catalytic properties enhances reaction efficiency and selectivity. Overall, MOFs' structural versatility and multifunctionality make them pivotal in addressing global challenges in energy, health, and environmental sustainability, with ongoing research expanding their potential across these domains.
Page(s):
15-15
DOI:
DOI not available
Published:
Journal: 4th International Conference of Sciences “Revamped Scientific Outlook of 21st Century, 2025” , November 12,2025, Volume: 1, Issue: 1, Year: 2025
Keywords:
drug delivery
,
catalysis
,
Gas Adsorption
,
MOFs