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Amyloidosis of the nasopharynx: an unexpected cause of unilateral middle ear effusion
Author(s):
1. Neil Mccluney: Department of Otolaryngology Head and Neck Surgery, University of Aberdeen, Aberdeen Royal Infirmary, Aberdeen, AB25 2ZN, UK
2. Muhammad Shakeel: Department of Otolaryngology Head and Neck Surgery, University of Aberdeen, Aberdeen Royal Infirmary, Aberdeen, AB25 2ZN, UK
3. Andrew Dallas: Department of Otolaryngology Head and Neck Surgery, University of Aberdeen, Aberdeen Royal Infirmary, Aberdeen, AB25 2ZN, UK
4. Akhtar Hussain: Department of Otolaryngology Head and Neck Surgery, University of Aberdeen, Aberdeen Royal Infirmary, Aberdeen, AB25 2ZN, UK
5. Andrea Chapman: Department of Histopathology, University of Aberdeen, Aberdeen Royal Infirmary, Aberdeen, AB25 2ZN, UK
Abstract:
Amyloidosis is an idiopathic disease that is characterized by the extracellular deposition of fibrillar proteins. The disease can be categorized as primary or secondary where deposits occur in conjunction with chronic diseases such as rheumatoid arthritis or tuberculosis. The deposits can be localized or systemically distributed. It can mimic, and also be associated with underlying malignancy. Primary amyloidosis is a rare cause of a nasopharyngeal lesion, and less so of a secondary middle ear effusion. Its association with underlying chronic and malignant disease must not be over-looked if serious complications are to be avoided. It is, therefore, important to consider this as a differential diagnosis in such patients.
Page(s): 706-707
DOI: DOI not available
Published: Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 21, Issue: 11, Year: 2011
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