Toxicopathological effects of endosulfan in female Japanese Quails (Coturnix japonica ) | [Advancements in life sciences • 2020]

Author(s):

1. Tahir Hussain: Faculty of Veterinary Science, University of Agriculture Faisalabad,Pakistan

2. Muhammad Kashif Saleemi: Faculty of Veterinary Science, University of Agriculture Faisalabad,Pakistan

3. Muhammad Zargham Khan: Faculty of Veterinary Science, University of Agriculture Faisalabad,Pakistan

4. Ahrar Khan: Faculty of Veterinary Science, University of Agriculture Faisalabad, Pakistan Shandong Vocational Animal Science and Veterinary College, Weifang, 261061, China

5. Rao Zahid Abbas: . Faculty of Veterinary Science, University of Agriculture Faisalabad,Pakistan

6. Muhammad Qamar Bilal: . Institute of Animal and Dairy Sciences, University of Agriculture Faisalabad,Pakistan

7. Farrah Deeba: . Faculty of Veterinary Science, University of Agriculture Faisalabad,Pakistan

8. Hamid Irshad: . PARC National Agricultural Research Center,Islamabad,Pakistan

9. Zahida Fatima: . PARC National Agricultural Research Center,Islamabad,Pakistan

10. Farhan Afzal: . Poultry Research Institute,Murree Road Rawalpindi,Pakistan

11. Umar Farooq: . Subcampus Toba Tek Singh, University of Agriculture Faisalabad,Pakistan

12. Muhammad Moazam Jalees: . Department of Microbiology Cholistan University of Veterinary and Animal Sciences,Bahawalpur,Pakistan

Abstract:

Background: The current study was planned to investigate the toxicopathological effects of endosulfan in female Japanese quails. ackground: The current study was planned to investigate the toxicopathological effects of endosulfan in Methods: A total of 120 quail of 4 weeks old were divided into six equal groups (A-F) and administered endosulfan in feed at dose rate of 0, 5, 25, 50, 100, and 500 mg/kg feed, respectively for 90 days. Parameters studied included clinical signs, feed intake, body weight and mortality. Hematology, serum biochemistry, hatchability and fertility were also determined. Gross and microscopic changes on different organs were recorded. Results: The quails of the group B did not show any clinical signs and had significantly lower values of feed intake, testes relative weight and leukocyte number than those of the control group A. The quails of group C and D had mild depression while those of the group E and F showed nervous excitation following ingestion of endosulfan. There was a dose related delay in onset of crowing, appearance of foamy material in the droppings. The feed intake, erythrocyte and leukocyte counts, hematocrit values, and serum total proteins of endosulfan fed quails were significantly (p < 0.05) lower than that of the group A. The total egg production in groups A, B and C was significantly higher from group D, E and F. The hatchability in group A and B was significantly higher from groups C, D, E and F. The difference of dead in shell % and early dead among different groups was nonsignificant. Infertile egg percentage was significantly higher in group E compared with all other groups except group F. The necrotic changes were observed in all parts of oviduct in high dose groups, similarly necrotic changes and vacuolar degeneration was observed in hepatic parenchyma in high dose groups D-F. Conclusion: It may be concluded that endosulfan leads to dose dependent changes in the quails.

Page(s): 72-78

DOI: DOI not available

Published: Journal: Advancements in life sciences, Volume: 7, Issue: 2, Year: 2020

Keywords:

histopathology , haematological values , body weight , Endosulfan , Coturnix japonica

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