The Use of Fetal Fibronectin and vaginal pH as new Laboratory Markers for Detection of Preterm Delivery in Iraq | [Pakistan Journal of Medical and Health Sciences • 2020]

Author(s):

1. ALI HATTEM HUSSAIN: Nursing Department, Technical College of Health, Sulaimani Polytechnic University,Sulaimnai City/,Iraq

2. YADGAR AZIZ ABDALLA: Nursing Department, Technical College of Health, Sulaimani Polytechnic University,Sulaimnai City/,Iraq

3. ROZHAN BAHAALDDIN ABDALLA: Nursing Department, Technical College of Health, Sulaimani Polytechnic University,Sulaimnai City/,Iraq

4. DENE SABIR ABDALLA: Nursing Department, Technical College of Health, Sulaimani Polytechnic University,Sulaimnai City/,Iraq

5. KOZHIN AZIZ BAIZ: Nursing Department, Technical College of Health, Sulaimani Polytechnic University,Sulaimnai City/,Iraq

6. BAHEZ ABALKARIM HAMARAHIM: Nursing Department, Technical College of Health, Sulaimani Polytechnic University,Sulaimnai City/,Iraq

7. MUHAMMAD KAMAL KARIM: Nursing Department, Technical College of Health, Sulaimani Polytechnic University,Sulaimnai City/,Iraq

Abstract:

Background: In Iraq, vaginal fFN and vaginal pH are not used in clinical settings as biomarkers to evaluate the preterm delivery. Aim: To evaluate the use of vaginal fFN test and measuring of vaginal pH in early prediction of preterm delivery. Methods: 37 pregnant women were enrolled in this study, 23 of them were patients group with suspected preterm delivery, while the remaining 14 pregnant women were a control group. Vaginal speculum and vaginal swab were used to help in collecting the specimen, the cervicovaginal secretions, then after, these secretions were used for fFN testing by a fFN Rapid Test cassette /all test company/ China and to measure the vaginal pH by vaginal pH Rapid test /all test company/China. The demographic and clinical data were obtained by a questionnaire. Results: the result of the current study showed that 12(52.2%) of patients' group were positive for vaginal fFN, while the other 11 (47.8%) of this group were negative; all pregnant women in the control group were negative for vaginal fFN. Sixteen (70%) of patients' group and 10(71%) of control group have an elevated vaginal pH. PTL was the outcome in 12/12 (100%) of patients positive for fFN and in 4 patients negative for fFN, while all control group were completed full term labor. In the patients' group, fetal death or health problems are more frequent in positive fFN (7/12 (58%)) than in fFN negative (0/11 (0%)). There is no statistical differences regarding ages, clinical features, and type of delivery in fFN positive or negative and in high vaginal pH or normal pH. Conclusions : vaginal fFN is an important biomarker for predicting PTL and fetal health, while high vaginal pH is a common finding in most of pregnant women whether they are at risk of PTL or normal pregnancy. The age of pregnant women, clinical features, and the type of delivery have no relation to vaginal fFN positivity or to high vaginal pH.

Page(s): 793-795

DOI: DOI not available

Published: Journal: Pakistan Journal of Medical and Health Sciences, Volume: 14, Issue: 2, Year: 2020

Keywords:

pregnancy , Vaginal pH , Fibronectin , preterm labor

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