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Adverse Effects of Cypermethrin on the Chick (Galus domesticus) Development Are Reversed by Co-treatment with Vitamin E and Olive Oil.
Author(s):
1. Khawaja Raees Ahmad: Department of Zoology, University of Sargodha, Sargodha, Pakistan
2. Kamran Shehry: Department of Zoology, University of Sargodha, Sargodha, Pakistan
3. Kausar Raees: Government College for Women Farooq Colony, Sargodha, Pakistan
4. Muhammad Ali Kanwal: Department of Zoology, University of Sargodha, Sargodha, Pakistan
5. Tahir Abbas: Biology Department, Government College, Kot-Momin District: Sargodha, Pakistan
6. Asmat Ullah: Department of Zoology University of the Punjab, Lahore, Pakistan
Abstract:
Cypermethrin (CN) is a type II pyrethroid insecticide that has recently been implicated in reproductive and developmental disorders. The aim of present study was to discover the potential role of vitamin E (vitE) and Olive oil (O) in alleviation of prenatal developmental abnormalities of CN exposure in the domestic chick. Fertilized eggs (60 each) were assigned to vehicle (C); CN, CNO, CNE and CNOE treated groups. Embryos from 20 eggs in each group were recovered on 7, 14 and 21days of incubation. Mean body weight of the hatchlings and the rate of hatching were significantly higher (P=0.05) in all groups than that of the CN group. Abnormalities of in ovo CN exposure in 7 days old embryos included: growth retardation, reduced beak, microphthalmia, microcephaly, open eyes, abdominal edema and limb deformities. While the 14 and 21 days old embryos exhibited patchy plumage, congenital glaucoma, spina bifida occulta, and limb deformities. Rate of occurrence of these abnormalities were decreased with co-treatment of CN with olive oil or/and vitE. It was thus concluded that CN contained potent avian developmental disruption potentials while the co-treatment of vitamin E and/or olive oil have been found to curtail the chances of CN induced embryonic disruptions in developing chick.
Page(s): 46-50
DOI: DOI not available
Published: Journal: Pakistan Veterinary Journal, Volume: 38, Issue: 1, Year: 2018
Keywords:
Vitamin E , Teratogenesis , Cypermethrin , Olive oil
References:
[1] AbdEl-Aziz,GS , El-Fark,MM and Saleh,HA,Rec,,2012,The prenatal toxic effect of methylmercury on the development of the appendicular skeleton of rat fetuses and the protective role of vitamin E,,295,939,49
[2] Abdul-HamidM,MoustafaN,AsranAEMAA,,2017,Cypermethrin-induced histopathological, ultrastructural and biochemical changes in liver of albino rats: The protective role of propolis and curcumin,Beni-Suef Uni J Basic Appl Sci,6,160,73
[3] AbhilashPC,SinghN,,2009,Pesticide use and application: An Indian scenario,J Hazard Mater,165,1,12
[4] AhmadL,KhanA,MZ Khan,,2012,Toxico-pathological effects of cypermethrin upon male reproductive system in rabbits,Exp Toxicol Pathol,103,194,201
[5] AslamF,KhanA,KhanMZ,,2010,Toxico-pathological changes induced by cypermethrin in broiler chicks: their attenuation with vitamin E and selenium,Exp Toxicol Pathol,62,441,50
[6] AydinR,ParizaMW,CookME,,2011,Olive oil prevents the adverse effects of dietary conjugated linoleic acid on chick hatchability and egg quality,J Nutr,131,800,6
[7] BeauchampGK,KeastRS,MorelD,,2005,Phytochemistry: ibuprofen like activity in extra virgin olive oil,Nature,437,45,6
[8] FaragAT,GodaNF,ShaabanNA,,2007,Effects of oral exposure of synthetic pyrethroid, cypermethrin on the behavior of F1 progeny in mice,Reprod Toxicol,23,560,7
[9] FitóM,de la TorreR,CovasMI,,2007,Olive oil and oxidative stress,Mol Nutr Food Res,51,1215,24
[10] HuangF,LiuQ,XieS,,2016,Cypermethrin induces macrophages death through cell cycle arrest and oxidative stress-mediated JNK/ERK signaling regulated apoptosis,Int J Mol Sci,17,885,
[11] JinY,ZhengS,PuY,,2011,Cypermethrin has the potential to induce hepatic oxidative stress, DNA damage and apoptosis in adult zebrafish (Danio rerio),Chemosphere,82,398,404
[12] KhanA,AhmadL,KhanMZ,,2012,Hemato-biochemical changes induced by pyrethroid insecticides in avian, fish and mammalian species,Int J Agri Biol,14,834,42
[13] MaduEP,,2015,Teratogenic and embryotoxic effects of orally administered cypermethrin in pregnant albino rats,J Toxicol Environ Health Sci,7,60,7
[14] MathurP,DingZ,SaldeenT,,2015,Tocopherols in the prevention and treatment of atherosclerosis and related cardiovascular disease,Clin Cardiol,38,570,6
[15] Oliveras-LópezMJ,BernáG,CarneiroEM,,2008,An extra virgin olive oil rich in polyphenolic compounds has antioxidant effects in OF1 mice,J Nutr,138,1074,8
[16] Oliveras-LópezMJ,BernáG,Jurado-RuizE,,2014,Consumption of extra virgin olive oil rich in phenolic compounds has beneficial antioxidant effects in healthy human adults,J Funct Foods,10,475,84
[17] PrustyAK,MeenaDK,MohapatraS,,2015,Synthetic pyrethroids (Type II) and freshwater fish culture: Perils and mitigations,Int Aquat Res,7,163,91
[18] RahmanT,HosenI,IslamMMT,,2012,Oxidative stress and human health,Adv Biosci Biotechnol,3,997,1019
[19] RahmaniAH,AlbuttiAS,AlySM,,2014,Therapeutics role of olive fruits/oil in the prevention of diseases via modulation of anti-oxidant, anti-tumour and genetic activity,Int J Clin Exp Med,7,799,808
[20] RichterovaZ,MachovaJ,StaraA,,2015,Effects of a cypermethrinbased pesticide on early life stages of common carp (Cyprinus carpio L.),Vet Med,60,423,31
[21] SharafS,KhanA,KhanMZ,,2010,Clinico-hematological and micronuclear changes induced by cypermethrin in broiler chicks: Their attenuation with vitamin E and selenium,Exp Toxicol Pathol,62,333,41
[22] ShiX,GuA,JiG,,2011,Developmental toxicity of cypermethrin in embryo-larval stages of zebrafish,Chemosphere,85,1010,6
[23] SvartzGV,AronzonCM,Pérez CollCS,,2016,Combined endosulfan and cypermethrin-induced toxicity to embryo-larval development of Rhinella arenarum,J Toxicol Environ Health A,79,197,209
[24] UgginiGK,SureshB,,2013,Genotoxic effects of two different classes of insecticide in developing chick embryos,Toxicol Environ Chem,95,992,1005
[25] UgginiGK,PatelPV,BalakrishnanS,,2012,Embryotoxic and teratogenic effects of pesticides in chick embryos: a comparative study using two commercial formulations,Environ Toxicol,27,166,74
[26] UllahMS,AhmadM,AhmadN,,2006,Toxic effects of cypermethrin in female rabbits,Pak Vet J,26,193,6
[27] WuC,ZhangY,ChaiL,,2017,Oxidative stress, endocrine disruption, and malformation of Bufo gargarizans embryo exposed to sub-lethal cadmium concentrations,Environ Toxicol Pharmacol,49,97,104
[28] YangY,MaH,ZhouJ,,2014,Joint toxicity of permethrin and cypermethrin at sublethal concentrations to the embryo-larval zebrafish,Chemosphere,96,146,54
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