Author(s):
1. Amima Asif Ghouri:
Department of Pharmacognosy, University of Karachi, Karachi, 75270, Pakistan
2. Sadia Ghousia Baig:
Department of Pharmacology, University of Karachi, Karachi, 75270, Pakistan
3. Muhammad Mohtasheem ul Hasan:
Department of Pharmacognosy, University of Karachi, Karachi, 75270, Pakistan
Abstract:
Anxiety is defined as the disorder involving excessive, irrational fear and worry. In 2022, approximately 30% of the men and 37% of the women were reported with high levels of anxiety. According to WHO, 70-80% population of developing countries still believes in non-conventional medicine, predominantly from plant origin and 40% of pharmaceutical formulations consist of natural products. The current study was therefore designed to assess the anxiolytic activity of Trapa bispinosa Roxb., commonly known as water chestnut. The ethanolic extract was prepared from the fruit kernel and its anxiolytic study was conducted on Swiss Albino mice. The extract was orally administered to the experimental animals and the time spent in the light box was analysed, using the light and dark box model. The results were significant and better as compared to the drugs available in the market. This indicated the potential of Trapa kernel as a natural anxiolytic agent.
Page(s):
79-79
DOI:
DOI not available
Published:
Journal: Abstract Book on International Conference on Food and Applied Sciences (ICFAS-23) 3-5 August 23, Volume: 0, Issue: 0, Year: 2023
Keywords:
Anxiolytic
,
kernel
,
water chestnut
,
Trapa bispinosa
,
nonconventional medicine
References:
References are not available for this document.
Citations
Citations are not available for this document.