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Formulation Development and in-vitro in-vivo characterization of Topical Carbopol Based Aqua Gel Containing Plant Extracts as Wound Dressing
Author(s):
1. Barkat A Khan: Drug Delivery and Cosmetics Lab (DDCL), GCPS, Faculty of Pharmacy, Gomal University, D.I. Khan, Paksitan
2. Nauman Ahmed: Drug Delivery and Cosmetics Lab (DDCL), GCPS, Faculty of Pharmacy, Gomal University, D.I. Khan, Paksitan
Abstract:
Burn wound healing is a complex and multistep process. Proper and complete healing requires adequate moisture, microbial prevention, exudates absorption, and scab formation prevention at the wound bed. Aqua-gel is a suitable carrier system that possess all above mention characteristics for burn wound healing. In this study, Carbopol 934 and polyethylene glycol based aqua-gel was designed by incorporating 2% Calotropis gigantea extract. Various formulations were developed and F2 was considered Optimized while it was subjected to FTIR analysis, Scanning electron microscope, HPLC content determination, rheological behaviors, invitro release & release kinetics, pH and swelling behaviours. The results demonstrated that Calotropis gigantea loaded aqua-gel has great potential to increase the burn wound healing rate as compared to control group
Page(s): 90-90
DOI: DOI not available
Published: Journal: Abstract Book on International Conference on Life Sciences (ICLS-23) 11-12 May 22-23, Volume: 0, Issue: 0, Year: 2023
Keywords:
Topical Carbopol , Aqua Gel Containing Plant Extracts
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