Total Polyphenolic Compounds, Total Flavonoids, GC-MS Analysis of Volatile Constituents, Evaluation of Antioxidant and Antimicrobial Activities of Prunus dulcis Nuts. | [Pakistan Journal of Pharmaceutical Sciences • 2019]

Author(s):

1. Muhammad Nasimullah Qureshi: Department of Chemistry, University of Swabi, Swabi, Pakistan; Department of Chemistry, Abdul Wali Khan University, Mardan, Pakistan; Key Laboratory of Plant Resources and Chemistry in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, PR China

2. Sodik Numonov: Key Laboratory of Plant Resources and Chemistry in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, PR China; Key Laboratory of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, P. R. China; State Scientifically-Experimental and Production Or

3. Haji Akber Aisa: Key Laboratory of Plant Resources and Chemistry in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, PR China; Key Laboratory of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, P. R. China

Abstract:

Prunus dulcis has been known as a source of nutrients in many traditional foods and as a source of important biologically active compounds in traditional medicines. The present study describes the determination of total polyphenolic compounds, total flavonoids and GC-MS analysis of hexane and chloroform fractions of 70% ethanol extract of whole almond shelled seed. Antioxidant and antimicrobial activities of various extracts of the nuts were evaluated. Folin-Ciocalteau procedure resulted in total polyphenolic compounds as 0.008 mg (gallic acid equivalents)/mg of the dried extract and amount of total flavonoids contents yielded were 0.001 mg (quercetin equivalents)/mg of the nuts dried extracts. GC-MS analysis of the hexane and chloroform fractions yielded a number of volatile constituents, resulting in highest amounts of 6-Octadecenoic acid and 1,1,3,3-Tetramethyl cyclopentane as 37.52% and 24.54% in hexane and chloroform fractions respectively. Antioxidant activity using the DPPH radical scavenging assay resulted in very low activity in all the extracts. Only n-butanol extract showed mild activity against the gram negative E. coli with inhibition zone diameter 8 mm while rest of samples did not show any activity against any microbial strains under study.

Page(s): 1461-1466

DOI: DOI not available

Published: Journal: Pakistan Journal of Pharmaceutical Sciences, Volume: 32, Issue: 4, Year: 2019

Keywords:

total polyphenolics and flavonoids contents

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