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Validation of some of the ethnopharmacological uses of Xanthium strumarium and Duchesnea indica .
Author(s):
1. Fazli-Khuda: Department of Pharmacy, University of Peshawar, Peshawar, 25120, Pakistan
2. Zafar Iqbal: Department of Pharmacy, University of Peshawar, Peshawar, 25120, Pakistan
3. Ayub Khan: Department of Chemistry, Kohat University of Science and Technology, Kohat, 26000, Pakistan
4. Zakiullah: Department of Pharmacy, University of Peshawar, Peshawar, 25120, Pakistan
5. Fazli Nasir: Department of Pharmacy, University of Peshawar, Peshawar, 25120, Pakistan
6. Muhammad Shafiq Khan: Department of Pharmacy, Hazara University, Mansehra, Pakistan
Abstract:
The antimicrobial potential of alcoholic extract and various fractions of Xanthium strumarium (XS) and Duchesnea indica (DI) against different strains of bacteria and fungi was investigated. The chloroform fraction from Xanthium strumarium was found to be the most active among the fractions, showing good activity against Escherichia coli, Shigella flexneri, Bacillus subtilus and Staphylococcus aureus. Interestingly, most of the activity detected was against gram-positive (Staphylococcus aureus) bacteria. The chloroform fraction exhibited significant antibacterial activity (19 mm zone of inhibition) against gram negative (Shigella flexneri), bacteria. Promising level of antifungal activity was observed in all fractions against Aspergillus flavus, Fusarium solani and Microsporum canis. Looking to these results it may be concluded that Xanthium strumarium and Duchesnea indica can be a potential source for activity guided isolation of lead compounds with antimicrobial properties.
Page(s): 1199-1201
DOI: DOI not available
Published: Journal: Pakistan Journal of Botany, Volume: 44, Issue: 4, Year: 2012
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