A COMPARATIVE ANALYSIS OF IN-HOSPITAL LEFT VENTRICULAR FUNCTION IN PATIENTS WITH SUCCESSFUL OR UNSUCCESSFUL STREPTOKINASE THROMBOLYSIS FOLLOWING ACUTE MYOCARDIAL INFARCTION | [Journal of Postgraduate Medical Institute • 2012]

Author(s):

1. Sher Bahadar Khan: Department of Cardiology Lady Reading Hospital,Peshawar ,Pakistan

2. Rafiullah: Department of Cardiology Lady Reading Hospital,Peshawar ,Pakistan

3. Hafiz ur Rehman: Department of Cardiology Lady Reading Hospital,Peshawar ,Pakistan

4. Tariq Nawaz: Department of Cardiology Lady Reading Hospital,Peshawar ,Pakistan

5. Syed Tahir Shah: Department of Cardiology Lady Reading Hospital,Peshawar ,Pakistan

6. Syed Sadiq Shah: Department of Cardiology Lady Reading Hospital,Peshawar ,Pakistan

7. Hameedullah: Department of Cardiology Lady Reading Hospital,Peshawar ,Pakistan

8. Abdul Hadi: Department of Cardiology Lady Reading Hospital,Peshawar ,Pakistan

9. Muhammad Hafizullah: Department of Cardiology Lady Reading Hospital,Peshawar ,Pakistan

10. Adnan Mahmood Gul: Department of Cardiology Lady Reading Hospital,Peshawar ,Pakistan

11. Hikmatullah Jan: Department of Cardiology Lady Reading Hospital,Peshawar ,Pakistan

12. Syed Farhat Abbas Shah: Department of Cardiology Lady Reading Hospital,Peshawar ,Pakistan

Abstract:

To compare in-hospital left ventricular function in patients with unsuccessful and successful thrombolysis presenting with acute myocardial infarction treated with streptokinase. Methodology: This comparative study was conducted at department of Cardiology, Lady Reading Hospital Peshawar, from October 2006 to October 2007. Two hundred patients with first acute myocardial infarction were divided into two groups: group A (successful thrombolysis) and group B (unsuccessful thrombolysis), using ECG criteria. To determine Left Ventricular Function, 2-D Echo was used. Results: Group A included 136 (68%) patients and group B included 64 (32%) patients. Impaired left ventricular function was found in 41 (30.1%) patients in group A and 41 (64.1%) patients in group B (p< 0.001). Left ventricular failure was present in 31 (22.8%) patients of group A and 30 (46.9%) patients of group B (p=0.001). Cardiogenic shock was diagnosed in 2 (1.5%) patients in group A and 6 (9.4%) patients in group B (p=0.008). Conclusion: Presence of LVF is strongly associated with unsuccessful thrombolytic therapy in this group of patients.

Page(s): 134-137

DOI: DOI not available

Published: Journal: Journal of Postgraduate Medical Institute, Volume: 26, Issue: 2, Year: 2012

Keywords:

Myocardial Infarction , Diagnosis , thrombolysis

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