Thermodynamic dissociation constant studies of caffeine at different temperatures and in organic water solvent mixture. | [Pakistan Journal of Pharmaceutical Sciences • 2004]

Author(s):

1. Saeeduddin: Shah Abdul Latif College Mirpurkhas (Sindh), Pakistan

2. A. W. K. Khanzada: National Centre of Excellence in Analytical Chemistry University of Sindh, Jamshoro, Pakistan

Abstract:

Thermodynamic dissociation studies have been carried out potentiometrically at various temperatures from 25 to 50°C and in 10, 20, 30 and 40% v/v dioxane-water solvent mixture at 25 C. The influence of temperature and nature of solvent on dissociation equilibria of caffeine is being investigated A computer program in GW-BASIC has been used to calculate the pK values.

Page(s): 83-87

DOI: DOI not available

Published: Journal: Pakistan Journal of Pharmaceutical Sciences, Volume: 17, Issue: 1, Year: 2004

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