A comparison Between Intrathecal Isobaric Levobupivacaine 0.5% and Isobaric Ropivacaine 0.5% in Lower Limb Surgeries: a Prospective, Randomized, Double Blind Study. | [Anaesthesia, Pain and Intensive Care • 2018]

Author(s):

1. KajalA Bhatt: Department of Anesthesiology, GMERS Medical College, Ahmedabad, Gujarat, India

2. IlaA Prajapati: Department of Anesthesiology, GMERS Medical College, Ahmedabad, Gujarat, India

Abstract:

Background & Objectives: Levobupivacaine and ropivacaine are the two recently introduced local anesthetics alternatives to bupivacaine in clinical practice. The present study has been conducted to compare the efficacy of intrathecal isobaric levobupivacaine 0.5% and isobaric ropivacaine 0.5% in terms of sensory and motor blockade characteristics, intraoperative hemodynamics stability and side effects if any. Methodology: A prospective randomized double blind study was conducted in 60 ASA grade I-II patients in age groups of 18-60 years undergoing lower limb surgeries. Patients were divided in 2 groups of 30 patients each. Group L received 3 ml isobaric levobupivacaine 0.5%, whereas patients in Group R received 3 ml isobaric ropivacaine intrathecally. Patients were assessed for onset and duration of sensory and motor blockade, intraoperative hemodynamic parameters and side efects. Results: There was no diference in demographic data, onset and peak effect of sensory and motor block in both groups (p > 0.05). Duration of sensory and motor block and time to two segment regression were significantly longer in Group L than Group R (p < 0.001). Intraoperative hemodynamic parameters showed no statistical significance in both groups without any appreciable side efects. Conclusion: We conclude that both levobupivacaine and ropivacaine are effective with stable hemodynamics without significant side effects when used intrathecally. Ropivacaine has shorter duration of sensory and motor blockade than levobupivacaine.

Page(s): 93-97

DOI: DOI not available

Published: Journal: Anaesthesia, Pain and Intensive Care, Volume: 22, Issue: 1, Year: 2018

Keywords:

Spinal , Anesthesia , Ropivacaine , Levobupivacaine

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