Yield of Gene Expert and ZN Staing in diagnosis of Pulmonary and Extra Pulmonary Tuberculosis | Pakistan Journal of Medical and Health Sciences 2020

Author(s)

Nabi Rehman Mardan Medical Complex /Bacha Khan Medical Complex, Swabi, Pakistan

Muhammad Haroon Taj Khyebr Medical University Institute of Medical Sciences (Khyber Institute of Medical Sciences),Kohat, Pakistan

Ajmaal Jami Isra Medical University Karachi, Pakistan

Aneela Qureshi IsraMedical University,Karachi, Pakistan

M Zahid Shah Baqai Medical University Karachi, Pakistan

Noor Khaliq Jan Naseer Ullah Khan Babar Memorial Teaching Hospital Kohat Road Peshawer, Pakistan

Abstract

Objective: To determine the prevalence of pulmonary and multi drug resistant TB in patients visited outpatients for respiratory problems. Study Design: Descriptive, Cross-Sectional Place and Duration: Conducted at Medicine Department of Mardan Medical complex, Bacha Khan Medical College, Mardan for duration of one year from 15st January 2019 to 14 January, 2020. Methods: Total 4600 patients were included in this study. Patients were divided into two groups. Group A had 1100 patients and treated by Gene Xpert technique and the group B had 3500 patients checked by Zhiel Neelsen (ZN) Staining. Patients detailed demographics were age, sex were recorded after taking written consent. Complete data was analyzed by SPSS 24.0 version. Results: Out of 1100 patients in group A 715 (665%) were males and 385 (35%) patients were females, and MTB was detected in 320 (29.09%) patients. In group B 2400 (68.6%)patients were males and 1100 (31.4%) were females, out of these 430 (12.3%) cases showed smear positive. Frequency of rifampicin was 20 (6.25%) out of 320 patients of MTB. Conclusion: We concluded in this study that gene Xpert is effective for diagnosis of tuberculosis and drug resistant TB while smear positive had many other advantages.

Publication Details

Page(s) 1950-1951

DOI DOI not available

Published Journal: Pakistan Journal of Medical and Health Sciences, Volume: 14, Issue: 4, Year: 2020

Keywords

Tuberculosis Multidrug resistant TB ZN Staining gene xpert

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