Zwitterion Chromatography-Hydrophilic Interaction Chromatography for Separation and Quantitative of Rutin and Quercetin from Herbs and Bee Products | Journal of Chemical Society of Pakistan 2021

Author(s)

Raad Radi Karabat Ministry of Education, Baghdad, Iraq

Ashraf Saad Rasheed Department of Chemistry, College of Science, University of Baghdad, Al-Jadriya campus, 10071 Baghdad, Iraq.

Mohammed Jasim M. Hassan Department of Chemistry, College of Science,Al-Mustansiriyah, Baghdad,Iraq

Abstract

Summary: Quercetin and rutin have a number of useful pharmacological consequences and a possible medication of the future. The growth of cancer cells was observed in vitro and the production of tumors in experimental animals was decreased. In addition to preventing human cancer induction and progression. A set of four HILIC stationary phases, two home-made columns with different space chains between the ionic site groups, and two commercially stationary phases HALO®HILIC 2.7 and ZIC®-pHILIC for chromatographic separation and quantitation of quercetin and rutin in herbs and bee products. The separation mechanisms are based on hydrophobic and hydrophilic for the quercetin and rutin, respectively. The validated method was successfully applied in bee products and herbs. The results showed that the HILIC methods were simple and reliable and could be used in bee products and herbs to detect the content of quercetin and rutin.

Publication Details

Page(s) 484-492

DOI DOI not available

Published Journal: Journal of Chemical Society of Pakistan, Volume: 43, Issue: 4, Year: 2021

Keywords

Rutin Quercetin Hydrophilic interaction Herbs Bee products

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